Bepanthen cream 5% tube 30 g

Pharmacodynamics. Dexpanthenol is the active substance of Bepanthen Cream, which is quickly converted into pantothenic acid in cells and acts as a vitamin. dexpanthenol is better absorbed than pantothenic acid when applied topically.

Pantothenic acid is a component of the essential coenzyme A (CoA). In this form of acetyl coenzyme A, coenzyme A plays an important role in the metabolism of every cell. Pantothenic acid is thus necessary for the restoration and regeneration of damaged skin and mucous membranes.

Pharmacokinetics. Dexpanthenol is quickly absorbed by the skin, after which it immediately turns into pantothenic acid and is added to the internal depot of this vitamin.

In the blood, pantothenic acid binds to blood plasma proteins (mainly albumin and β-globulins). In healthy adults, its concentration is approximately 500-1000 μg/l and 100 μg/l in blood and blood plasma, respectively.

Pantothenic acid is not metabolized in the body and is excreted unchanged. After oral administration, 60-70% of the drug dose is excreted in urine, the rest – in feces. In adults, 2-7 mg of pantothenic acid is excreted in the urine per day, in children – 2-3 mg.

Bepanthen cream is used in the following cases:

• for preventive treatment of dry, reddened or cracked skin;
• to accelerate the healing and epithelization of the skin in case of micro-injuries (mild burns and scratches), in case of skin irritation (for example due to radio, phototherapy or irradiation with ultraviolet rays), in case of diaper dermatitis, chronic skin ulcers and bedsores, anal fissures, erosion of the cervix and after transplantation skin;
• for the treatment of the skin of patients during and after the topical application of corticosteroids.
• for regular preventive care of the mammary glands in women who are breastfeeding, and for the treatment of nipple irritation and cracks.

Acceleration of healing and epithelization, regular skin care: use Bepanthen cream 1 or more times a day if necessary.

Care of the mammary glands of women who are breastfeeding: apply cream to the nipples after each breastfeeding.

Treatment of defects of the mucous membrane of the cervix: apply the cream 1 or several times a day under the supervision of a doctor.

Baby care: use Bepanthen cream after each diaper change.

Bepanthen cream quickly penetrates the skin, so it is suitable for the care of wet wounds, unprotected skin surfaces (face) and skin covered with hair. It is easily distributed over the surface, so it is suitable for the treatment of painful sunburns and other mild burns.

Hypersensitivity to dexpanthenol or other components of the drug.

From the side of the immune system, as well as the skin and subcutaneous tissues: there are reports of allergic reactions and allergic reactions from the skin: contact dermatitis, allergic dermatitis, itching, erythema, eczema, rash, urticaria, skin irritation and blistering.

When using the drug, contact with the eyes should be avoided.

Cetyl alcohol, stearyl alcohol, lanolin can cause local skin reactions (for example, contact dermatitis).

Propylene glycol can cause skin irritation.

The period of pregnancy and breastfeeding. There is no reason to believe that the use of the drug during pregnancy and breastfeeding is accompanied by a risk. During pregnancy, the drug should be used as prescribed by a doctor.

When used to treat cracked nipples during breastfeeding, the drug must be washed off before feeding.

Children. The drug is used in children of various age groups, including infants.

The ability to influence the speed of reaction when driving a motor vehicle or working with other mechanisms. Does not affect.

Cases of interaction with other medicinal products were not observed.

The active substance of Bepanthen cream, dexpanthenol, is well tolerated and, thus, is considered non-toxic in the literature. hypervitaminosis is not described.

At a temperature not higher than 25 °C.