Orasept oral spray 1.4% bottle 177 ml

Pharmacological properties

Pharmacodynamics.

The active substance of this drug is phenol; in low concentrations (from 0.25 to 1.5%) its water-glycerol solution is used as a local antiseptic (bactericidal and antifungal effect) and local anesthetic for treating the mucous membrane of the oral cavity and pharynx. Glycerin has a softening effect on the mucous membrane of the oral cavity.

Pharmacokinetics.

Phenol, which is part of the drug, is absorbed and excreted by mucus with subsequent excretion through the gastrointestinal tract. In case of overdose, phenol is metabolized in the liver and excreted by the kidneys.

Indications

As an analgesic and antiseptic:

• for infectious and inflammatory diseases of the oral cavity and pharynx (angina, pharyngitis, tonsillitis, stomatitis, gingivitis, periodontitis);
• after manipulations in the oral cavity and pharynx, dental operations;
• when using dentures or orthodontic appliances.

Application

Spray in the oral cavity and / or pharynx, the liquid can be swallowed. when used in the oral cavity – hold in the mouth for 15 seconds, then remove. for children aged 2 to 12 years, spray by pressing the bottle sprayer 3 times. for children aged 12 years and adults – by pressing 5 times. repeat spraying every 2-4 hours or according to the doctor’s recommendations. the duration of use is determined by the clinical effect and tolerability of the drug. if a dose of phenol in the form of a spray is missed, and the patient uses it regularly, the drug can be used when the patient remembers it. in the event that the time of the next dose is approaching, it is not recommended to use a double dose without consulting a doctor. the duration of treatment for uncomplicated angina should not exceed 7 days.

Contraindications

Individual hypersensitivity to the drug. Severe liver or kidney dysfunction. Phenol should not be used in the form of a throat spray in patients with inflammation of the epiglottis, inflammatory diseases with widespread damage to the mucous membranes.

Side effects

From the immune system. allergic reactions.

From the skin and subcutaneous tissues. Urticaria, itching, angioedema, rash. Possible reactions at the site of application, local swelling of the throat.

From the kidneys and urinary tract. Chromaturia (dark brown or green urine color).

Special instructions

The spray is intended for short-term use. If the symptoms of the disease do not pass within 7 days, this may indicate the presence of organic pathology (abscess, neoplasm), which requires other methods of treatment. A doctor’s consultation is necessary within 1-2 days in case of severe sore throat and/or symptoms such as fever, headache, rash, nausea or vomiting. If the condition worsens, you should immediately consult a doctor.

The concentration of phenol in the drug is recognized as safe in terms of toxicity or oncogenicity. Orasept does not have a harmful effect on tooth enamel.

Use during pregnancy and breastfeeding. Data on the use of phenol during pregnancy are absent or limited (less than 300 cases of treatment of pregnant women).

The results of the studies do not indicate the presence of direct or indirect reproductive toxicity when the drug is dosed according to the recommendations.

If it is necessary to use the drug during pregnancy, a doctor should be consulted.

Breastfeeding

It is not known whether phenol is excreted in breast milk. Therefore, a risk to newborns/infants cannot be excluded.

The ability to influence the reaction rate when driving vehicles or working with other mechanisms. Does not affect.

Children. In children under 12 years of age, this product should be used under adult supervision. The drug should not be used in children under 2 years of age.

Interactions

The drug is prescribed in the complex therapy of inflammatory diseases of the oral cavity and throat together with sulfonamides, antibiotics, vitamins.

Without consulting a doctor, the drug should not be used simultaneously with drugs for the treatment of myasthenia gravis; drugs that suppress the CNS; disinfectant solutions containing heavy metals; MAO inhibitors; neuromuscular transmission blockers; precipitation; vasoconstrictors.

Overdose

When ingested, phenol causes damage to the mucous membranes, nausea, vomiting, increased sweating, diarrhea. Dizziness and weakness are possible. At first, excitement may occur, followed by loss of consciousness. Central nervous system depression with circulatory and respiratory depression is noted. In severe cases, pulmonary edema, liver or kidney damage may develop, leading to impaired function of these organs. Death occurs due to respiratory failure, the lethal dose is 1-15 g of phenol taken orally. In case of overdose, symptomatic treatment is recommended (gastric lavage, administration of activated charcoal, if necessary, hospitalization in a toxicology department).

Storage conditions

Store at a temperature not exceeding 25 °C. Do not freeze.