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Glutargin consists of two active salts – arginine and glutamic acid. They play a major role in ensuring important biochemical processes of neutralization and excretion of the toxic metabolite – ammonia from the body. Glutamic acid promotes the transmission of nerve impulses in synapses, has an excitatory effect on the central nervous system, so the drug is used for neurotoxicosis. Glutargin exhibits hepatoprotective effects due to antioxidant, antihypoxic and membrane-stabilizing properties, has a positive effect on energy supply in hepatocytes.
Glutargin consists of two active salts – arginine and glutamic acid. They play a major role in ensuring important biochemical processes of neutralization and excretion of the toxic metabolite – ammonia from the body. Glutamic acid promotes the transmission of nerve impulses in synapses, has an excitatory effect on the central nervous system, so the drug is used for neurotoxicosis. Glutargin exhibits hepatoprotective effects due to antioxidant, antihypoxic and membrane-stabilizing properties, has a positive effect on energy supply in hepatocytes.
Garazone is actively used in alcohol intoxication, as it stimulates the utilization of alcohol in the monooxygenase system of the liver, prevents the inhibition of alcohol dehydrogenase; accelerates the inactivation and elimination of toxic products of ethanol metabolism.
Arginine improves blood circulation by eliminating capillary spasm and, together with glutamate, is a neurotransmitter. Arginine also helps reduce insulin resistance during pregnancy and stimulates metabolic processes in the placenta.
Glutargin is prescribed for the following diseases:
Usually, glutargin in tablet form is prescribed in a dose of 0.25 g 3 times a day, or a single dose of 0.75 g regardless of meals. In more severe cases, the dose can be increased to 8 g per day. The duration of treatment is from 2 to 3 weeks.
Intravenously drip glutargin is used in severe cases (vomiting, impaired consciousness) with hepatitis, alcohol poisoning or late gestosis of pregnant women at a dose of 10 ml per 150-200 ml of 0.9% sodium chloride solution or 5% glucose. With intramuscular administration, the standard dose is 5 ml 2 times a day.
In case of overdose, the following symptoms may occur: discomfort in the stomach area, nausea, chest pain, insomnia, and low blood pressure.
Treatment: symptomatic therapy, taking antihistamines, in severe cases – intravenous administration of glucocorticosteroids.
Glutargin solution should not be mixed with other medicinal solutions, except those recommended.
It should be prescribed with great caution to patients with cancer, as glutamate reduces the effect of anticancer drugs, especially vinblastine.
Glutargin may increase the secretion of insulin and growth hormone in patients with endocrine system disorders; this should be taken into account when prescribing the drug.
The active ingredient of the drug is arginine glutamate.
Store in the original packaging at a temperature not exceeding 25 °C, out of the reach of children.
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