Nazoferon nasal drops 100,000 IU/ml bottle of 5 ml

Pharmacodynamics. Nazoferon is an antiviral, antimicrobial, anti-inflammatory, immunomodulatory, antiproliferative agent. the biological effect of interferon is characterized by the following effects: antiviral – suppresses the replication of viruses (adenoviruses, influenza viruses) due to the inhibitory effect on transcription and translation processes; antiproliferative – inhibits cell reproduction (most DNA and RNA viruses). interferon initiates the synthesis of a specific protein kinase enzyme, which prevents translation due to the phosphorylation of one of the initiating factors of this process; activates a specific ribonuclease that damages the matrix RNA of the virus. the effects of interferon also include: stimulation of the production of other cytokines, induction of specific enzymes, suppression of cell proliferation, immunomodulation (increasing the phagocytic activity of macrophages and the specific cytotoxicity of lymphocytes against target cells). interferon is a mediator of immunity, has pronounced tissue specificity, protects the body from pathogens of infectious diseases.

Pharmacokinetics. Was not investigated.

Prevention and treatment of SARS in children aged 1 month and over (for nasal spray – from 1 year) and adults:

• in patients with frequent and long-term diseases of the upper respiratory tract;
• in contact with SARS patients;
• with hypothermia;
• with a seasonal increase in morbidity in organized groups (children and adults), in risk groups – medical workers, teachers, especially during an epidemic.

At the first signs of SARS (within 5 days):

• newborns and children aged 1 year – 1 drop 5 times a day (single dose – 8,000 IU, daily dose – 40,000 IU);
• children aged 1-3 years – 2 drops (spray doses *) 3-4 times a day (single dose: drops – 16,000 IU, spray – 20,000 IU, daily dose: drops – 48,000-64,000 IU , spray – 60,000-80,000 IU);
• children aged 3-14 years – 2 drops (spray doses) 4-5 times a day (single dose: drops – 16,000 IU, spray – 20,000 IU, daily dose: drops – 64,000-80,000 IU, spray – 80,000-100,000 IU);
• children aged 14-18 years – 2 drops (spray doses) 5-6 times a day (single dose: drops – 16,000 IU, spray – 20,000 IU, daily dose: drops – 80,000-96,000 IU, spray – 100,000-120,000 IU);
• adults – 3 drops (spray doses) 5-6 times a day (single dose: drops – 24,000 IU, spray – 30,000 IU, daily dose: drops – 120,000-144,000 IU, spray – 150,000-180 000 MO).

* In 1 drop = 1 short press on the dispenser.

For the prevention of respiratory viral infections. In case of contact with the patient and hypothermia – according to the age dosage 2 times for 5-7 days. If necessary, preventive courses are repeated. With one-time contact, one instillation (injection) is enough.

With a seasonal increase in morbidity – according to the age, the dosage is once in the morning with an interval of 1-2 days.

Hypersensitivity to interferon alfa-2b and other components of the drug, severe forms of allergic diseases in the anamnesis. period of pregnancy or breastfeeding.

In isolated cases – rash on the skin.

Nazoferon nasal spray. the drug contains methyl parahydroxybenzoate, which can cause allergic reactions, including delayed, in exceptional cases – bronchospasm.

The drug should not be used in case of violation of the integrity and labeling of the packaging, when the physical properties change (color or transparency of the liquid) and after the expiration date.

Individual use is recommended to prevent the spread of infection.

The procedure for using the nasal spray:

1. Remove the protective cap from the bottle.

2. Activate the sprayer by pressing (test spraying).

3. While in a vertical position, place the end of the nozzle one by one in each nostril and press the dosing pump.

4. After use, close the bottle with a cap.

Children. Use in children from 1 year of age.

Nazoferon nasal drops. The drug should be injected into each nostril.

Before using the drug, it is necessary to take a position lying on your back or sitting, slightly tilt your head back and turn to the side of the nasal passage into which the drops will be instilled, and, without touching the dropper of the bottle to the inner walls of the nose, instill the drug. Immediately after instillation, to evenly distribute the drug on the nasal mucosa, it is recommended to externally massage the wings of the nose with your fingers for several minutes.

The use of drops in children should be carried out under the supervision of adults.

The drug contains methylparahydroxybenzoate, which can cause allergic reactions, including delayed, in exceptional cases – bronchospasm.

The drug should not be used in case of violation of the integrity and labeling of the packaging, when the physical properties change (color or transparency of the liquid) and after the expiration date.

To avoid the spread of infection, individual use is recommended.

Avoid getting the drug on the mucous membrane of the eyes.

The procedure for using nasal drops in a bottle closed with a dropper:

1. Remove the protective cap from the bottle.

2. Turn the bottle with the nozzle down and before using the drops for the first time, make a few test presses on the dispenser pump.

3. Place the end of the nozzle one by one in each nostril and press the dosing pump the required number of times according to the dosage.

4. After use, close the bottle with a cap.

Children. Use in children aged from 1 month.

Nazoferon nasal spray / nasal drops

Use during pregnancy and breastfeeding. Use is contraindicated.

The ability to influence the speed of reaction when driving a motor vehicle or working with other mechanisms. Does not affect.

The simultaneous use of intranasal vasoconstrictor drugs is not recommended, as it leads to dryness of the nasal mucosa.

Was not investigated.

In a place protected from light at a temperature of 2-8 °C. shelf life after opening the bottle – 10 days.