Troxevasin gel 2% tube 40 g

Composition

active substance: troxerutin;

1 g of gel contains troxerutin 20 mg;

excipients: carbomer, triethanolamine, EDTA disodium salt, benzalkonium chloride, purified water.

Release form

Gel 2%.

Pharmacodynamics. Troxevasin is a mixture of bioflavonoids that contains at least 95% troxerutin. troxerutin accumulates selectively in the endothelial layer of venules, penetrates deeply into the subendothelial layer of the venous wall, and its concentration will be higher than in the surrounding tissues. the drug prevents damage to cell membranes caused by oxidation.

The antioxidant effect is manifested in the reduction and elimination of the oxidative properties of oxygen, inhibition of lipid peroxidation, protection of the vascular endothelium from the oxidative action of hydroxyl radicals. Troxerutin reduces the increased permeability of capillaries and increases the tone of veins. The protective effect is manifested in inhibition of activation and adhesion of neutrophils, reduction of erythrocyte aggregation and increase of resistance of erythrocytes to deformation, reduction of release of inflammatory mediators.

Troxevasin increases venous-arterial reflux, prolongs the time of repeated venous filling, improves microcirculation and microvascular perfusion.

The action of troxevasin is aimed at reducing swelling, pain, improving trophicity and eliminating various pathological disorders associated with venous insufficiency.

Pharmacokinetics. After local application of the drug, the active component is easily released from the water-soluble base of the gel and penetrates into the dermis after about 30 minutes, and into the subcutaneous fatty tissue after 2-5 hours.

Troxevasin gel is used for the symptomatic treatment of the following diseases:

• venous insufficiency;
• prevaricose and varicose syndrome;
• superficial thrombophlebitis, phlebitis and post-phlebitis conditions;
• complex treatment for hemorrhoidal diseases;
• swelling and pain in injuries and varicose veins;
• muscle cramps (convulsive contraction of the calf muscles).

Troxevasin gel is applied to the affected area in an even thin layer in the morning and in the evening, rubbing in light massage movements until the drug is completely absorbed. the gel has no smell and does not leave greasy stains on clothes. in severe cases, combined therapy with the use of troxevasin capsules is recommended. in case of chronic venous insufficiency, combined therapy is used until the symptoms are completely eliminated.

The dosage and duration of use of the medicinal product is determined by the doctor, taking into account the severity and course of the disease.

Children. There are no contraindications for the use of the drug in children.

Hypersensitivity to troxerutin or any excipient of the drug.

Troxevasin gel should not be applied to the mucous membrane, open wounds and eczematous areas of the skin.

When using troxevasin gel, allergic reactions are very rarely possible, including skin irritation, redness, itching, skin rashes, dermatitis, angioedema. usually these symptoms pass quickly after the withdrawal of the drug.

Benzalkonium chloride, which is part of the drug, irritates and can cause skin reactions.

Patients with severe kidney function disorders are not recommended to use the drug for a long time.

If the severity of the symptoms of the disease does not decrease when using the drug, you should consult a doctor.

Use during pregnancy and breastfeeding

There is no data on the adverse effects of the drug when used during pregnancy or breastfeeding. However, the use of Troxevasin gel in the first trimester of pregnancy is not recommended.

The ability to influence the speed of reaction when driving a motor vehicle or working with other mechanisms

Does not affect.

The drug enhances the effect of ascorbic acid on strengthening the structure and reducing the permeability of the vascular wall.

Cases of overdose have not been registered with local application. in case of accidental ingestion of a large amount of the drug, it is necessary to take general measures to remove the drug: induce vomiting, apply means for symptomatic treatment. if necessary, use peritoneal dialysis.

In the original packaging at a temperature not higher than 25 °C. Do not freeze.

Information about the drug for healthcare professionals.