Extended-release capsules “Aescusan Long” are used for chronic venous insufficiency:
- leg swelling;
- heaviness and pain in the legs, itching;
- calf muscle cramps.
Composition
One prolonged-release capsule contains (active ingredient) dry extract of horse chestnut seeds (Horse Chestnut Seeds Extract) (4.5-5.5: 1) (extractant ethanol 50% v/v) 240-290 mg, which corresponds to the content of triterpene glycosides in terms of anhydrous escin – 50 mg.
Excipients: dextrin, copovidone, talc, ammonium methacrylate copolymer (type A), ammonium methacrylate copolymer (type B), triethyl citrate.
The capsule shell contains black iron oxide (E172), red iron oxide (E172), yellow iron oxide (E172), titanium dioxide (E171), indigo carmine (E132), quinoline yellow (E104), gelatin, purified water, sodium dodecyl sulfate.
Contraindication
- hypersensitivity to dry extract from horse chestnut seeds and/or any component of the drug;
- renal failure.
Method of application
The drug is taken orally, one capsule 2 times a day (morning and evening) before meals. The capsules are swallowed whole, washed down with sufficient water. In case of minor stomach or intestinal disorders, it is recommended to take the capsules with meals.
The duration of treatment is determined by the doctor individually depending on the severity of the disease and the clinical effectiveness of the drug.
Application features
Pregnant women
Due to the lack of sufficient data, the use of the drug during pregnancy and breastfeeding is not recommended.
Children
The drug is not recommended for use in children (under 18 years of age) due to lack of safety data.
Drivers
The use of the drug does not affect the ability to drive a car or work with complex mechanisms.
Overdose
In case of overdose, the saponins contained in horse chestnut seeds can cause nausea, vomiting and diarrhea, drowsiness, delirium, mydriasis, and possible death as a result of respiratory paralysis after 24-48 hours.
Treatment: if there is no vomiting and a large amount of the drug has been taken, gastric lavage (for example, with a 0.02% potassium permanganate solution) and administration of activated charcoal are recommended; symptomatic treatment.
Side effects
On the part of the digestive system: infrequently (from ≥ 1/1000 and <1/100) – diarrhea, nausea and vomiting, gastrointestinal discomfort.
From the nervous system: infrequently (from ≥ 1/1000 and <1/100) – headache, dizziness.
Storage conditions
Store in the original packaging at a temperature not exceeding 25 °C, out of the reach of children.
Shelf life – 3 years.















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