Bepanthen cream 5% tube 30 g

Pharmacodynamics. Dexpanthenol – the active ingredient of the drug Bepanthen cream, is quickly converted into pantothenic acid in cells and acts as a vitamin. Dexpanthenol is better absorbed than pantothenic acid when applied topically.

Pantothenic acid is a component of the essential coenzyme A (CoA). In this form of acetyl-coenzyme A, coenzyme A plays an important role in the metabolism of every cell. Pantothenic acid is therefore essential for the repair and regeneration of damaged skin and mucous membranes.

Pharmacokinetics. Dexpanthenol is rapidly absorbed by the skin, after which it is immediately converted to pantothenic acid and added to the internal depot of this vitamin.

In the blood, pantothenic acid binds to plasma proteins (mainly albumin and β-globulins). In healthy adults, its concentration is approximately 500-1000 μg/L and 100 μg/L in blood and plasma, respectively.

Pantothenic acid is not metabolized in the body and is excreted unchanged. After oral administration, 60-70% of the dose is excreted in the urine, the rest in the feces. In adults, 2-7 mg of pantothenic acid is excreted in the urine per day, in children – 2-3 mg.

Bepanthen cream is used in the following cases:

• for preventive treatment of dry, red or cracked skin;
• to accelerate healing and epithelization of the skin in case of micro-damage (minor burns and scratches), in case of skin irritations (e.g. due to radio-, phototherapy or ultraviolet irradiation), in case of diaper dermatitis, chronic skin ulcers and bedsores, anal fissures, cervical erosion and after skin transplantation;
• for treating patients’ skin during and after topical application of corticosteroids.
• for regular preventive care of the mammary glands in breastfeeding women and for the treatment of irritation and cracked nipples.

Accelerate healing and epithelialization, regular skin care: apply Bepanthen cream 1 or more times a day as needed.

Breast care for breastfeeding women: apply cream to the nipples after each breastfeeding.

Treatment of cervical mucosal defects: apply the cream 1 or more times a day under the supervision of a doctor.

Baby care: apply Bepanthen cream after each diaper change.

Bepanthen cream penetrates the skin quickly, making it suitable for the care of weeping wounds, unprotected skin surfaces (face) and hairy skin. It spreads easily over the surface, making it suitable for the treatment of painful sunburn and other minor burns.

Hypersensitivity to dexpanthenol or other components of the drug.

On the part of the immune system, as well as the skin and subcutaneous tissues: there are reports of allergic reactions and allergic skin reactions: contact dermatitis, allergic dermatitis, itching, erythema, eczema, rash, urticaria, skin irritation and blistering.

When using the drug, contact with eyes should be avoided.

Cetyl alcohol, stearyl alcohol, lanolin may cause local skin reactions (e.g. contact dermatitis).

Propylene glycol may cause skin irritation.

Pregnancy and breastfeeding. There is no reason to believe that the use of the drug during pregnancy and breastfeeding is accompanied by risk. During pregnancy, the drug should be used as prescribed by a doctor.

When used to treat cracked nipples during breastfeeding, the drug must be washed off before feeding.

Children. The drug is used in children of different age groups, including infants.

The ability to influence the reaction speed when driving vehicles or working with other mechanisms. Does not affect.

No cases of interaction with other drugs were observed.

The active ingredient of Bepanthen cream, dexpanthenol, is well tolerated and is therefore considered non-toxic in the literature. Hypervitaminosis has not been described.

At a temperature not exceeding 25 °C.