Bilobil Intense capsules 120 mg 6 blisters of 10 pcs.

active ingredients:  1 capsule contains dry extract of ginkgo biloba leaves (Ginkgo biloba L., folium) (35-67:1) containing:

• 26.4-32.4 mg of flavonoids in the form of flavone glycosides;
• 3.36-4.08 mg of ginkgolides A, B, C;
• 3.12-3.84 mg of bilobalide – 120 mg;
• extractant – acetone;

excipients:  lactose monohydrate, corn starch, talc, colloidal anhydrous silicon dioxide, magnesium stearate, glucose solution;

shell:  gelatin, titanium dioxide (E 171), black iron oxide (E 172), red iron oxide (E 172), yellow iron oxide (E 172).

Cognitive deficits of various genesis (dyscirculatory encephalopathy due to stroke, traumatic brain injury, in old age, manifested by impaired attention and/or memory, decreased intellectual abilities, feelings of fear, sleep disturbances) and neurosensory deficits of various genesis (senile macular degeneration, diabetic retinopathy);

• lameness in chronic obliterating arteriopathy of the lower extremities (Fontaine stage II);
• visual impairment of vascular genesis, decreased visual acuity;
• hearing impairment, tinnitus, dizziness and impaired coordination, mainly of vascular origin;
• Raynaud’s syndrome.

Take 1 capsule 1-2 times a day during meals. Wash down with ½ glass of water. The average duration of the course of treatment is 3 months.

Cognitive disorders: prescribe 1 capsule of 120 mg 1-2 times a day. The duration of treatment is at least 8 weeks. After 3 months of therapy, the doctor should review the need for further use of the drug.

Peripheral arterial occlusive disease, as well as dizziness of vascular and involutional origin: prescribe 1 capsule of 120 mg 1 time per day. The duration of treatment is at least 8 weeks.

For dizziness, the duration of therapy is no more than 6-8 weeks.

The duration of tinnitus treatment is at least 12 weeks.

Hypersensitivity to ginkgo biloba extract or any inactive component of the drug.

From the nervous system: headache, dizziness, fainting (including vasovagal).

Gastrointestinal tract: dyspeptic phenomena, nausea, vomiting, gastrointestinal disorders, diarrhea, abdominal pain.

Immune system disorders: hypersensitivity reactions or allergic reactions, including angioedema, urticaria, shortness of breath.

Skin: skin inflammation, redness, swelling, rash, itching, eczema.

In rare cases, when using drugs containing ginkgo biloba extract, hemorrhages occur (gastrointestinal, eye, brain).

There is an increased likelihood of these side effects in case of concomitant therapy with anticoagulants (e.g. phenprocoumon, acetylsalicylic acid, coumarin anticoagulants) and non-steroidal anti-inflammatory drugs.

If any adverse reactions occur, you should stop using the drug and be sure to consult a doctor.

The first signs of improvement appear 1 month after the start of treatment.

In case of a pathologically increased tendency to bleed (hemorrhagic diathesis), as well as in the case of simultaneous use of anticoagulants, the drug should be taken only after consulting a doctor.

If an allergic reaction occurs, the patient should stop taking the drug.

Since there is evidence that preparations containing ginkgo biloba extract increase the tendency to bleed, taking Biloba Intens should be discontinued before surgical operations.

The drug contains lactose and glucose. Patients with rare hereditary forms of galactose intolerance, hereditary disorders – lactase deficiency or glucose-galactose malabsorption syndrome should not take this drug.

Use during pregnancy and breastfeeding. Due to the lack of clinical data, the drug is not recommended for use during pregnancy and breastfeeding.

Children. Since there is no sufficient experience with the use of the drug in children, treatment of children with Bilobil Intense is not recommended.

Ability to influence the reaction rate when driving vehicles or working with other mechanisms. During treatment, caution should be exercised when driving vehicles and engaging in other potentially hazardous activities that require increased concentration and speed of psychomotor reactions.

Concomitant use of NSAIDs is not recommended.

The drug should not be taken if the patient is taking acetylsalicylic acid, warfarin, or thiazide diuretics for a long time.

When used simultaneously with drugs that inhibit blood coagulation (such as phenprocoumon and acetylsalicylic acid), the effect of the latter may be enhanced – the risk of bleeding increases.

The simultaneous use of ginkgo biloba extract with the following drugs requires special supervision:

• Ginkgo biloba increases the metabolism of antiepileptic drugs that are metabolized through the CYP 2C enzyme system. When used simultaneously with antiepileptic drugs (valproate, phenytoin), they can lower the seizure threshold and increase the possibility of an epileptic seizure;
• drugs that are primarily metabolized by CYP 34A and have a narrow therapeutic index should be used with caution;
• The interaction of Ginkgo biloba extract with drugs that are metabolized by the cytochrome P450 enzyme system cannot be completely ruled out (in some cases, there is a possibility of inhibition or induction of some isoenzymes).

In case of overdose or R, dyspeptic disorders, impaired consciousness and headache may occur. Treatment is symptomatic.

Store at a temperature not exceeding 25 °C in the original packaging in order to protect from moisture. Keep out of the reach of children.