
$15.03
A new angioprotective drug produced by Ternopharm. Escuven gel contains escin, a substance first synthesized from horse chestnut seeds. Escuven gel has anti-inflammatory, antiexudative, capillary and venoprotective effects, increases vascular wall tone, reduces lymphostasis, eliminates venous congestion, and accelerates the resorption of post-traumatic and post-operative hematomas.
Active ingredient: aescin;
1 g of gel contains 10 mg of amorphous β-escin;
excipients: carbomer, propylene glycol, triethanolamine, methylparaben (E 218), ethanol 96%, purified water.
Gel 1%.
Pharmacodynamics. Escin is a natural mixture of triterpene saponins obtained from the seeds of horse chestnut (Aesculus hippocastanum L.), which have anti-edematous, venotonic properties and anti-inflammatory activity. In addition, escin acts at the initial stage of the inflammatory process associated with increased membrane and capillary permeability and the production of exudate in adjacent tissues. Escin exhibits antiserotonin and antihistamine effects. Escin inhibits the activity of prostaglandin synthetase. This enzyme is necessary for the formation of prostaglandins, which play an important role in the mechanism of inflammation. Escin prevents a decrease in the ATP content in endothelial cells and increases the activity of phospholipase A2, an enzyme responsible for the release of precursors of inflammatory mediators. Escin reduces the activity of lysosomal enzymes that break down proteoglycans contained in the capillary walls. This increases capillary resistance and reduces their permeability, thereby reducing the amount of exudate and the formation of edema.
Pharmacokinetics: Not studied.
Varicose veins, leg swelling and pain associated with venous insufficiency, post-traumatic hematomas and hematomas after injections and infusions.
Hypersensitivity to the components of the drug, skin damage (e.g., burns, eczema, open wounds).
Apply a thin layer of the gel to the damaged area of skin and around it 2-3 times a day. Do not rub in.
For varicose veins, the simultaneous use of an elastic bandage or elastic stockings is recommended.
The duration of treatment depends on the severity of the therapeutic effect. If after 14 days of therapy there is no improvement, you should consult a doctor.
Children. There is insufficient experience with the drug in children, so it is not recommended for use in patients of this age group.
Do not apply the gel to inflamed skin, open wounds and mucous membranes. Do not rub when applying. If skin inflammation, thrombophlebitis, severe pain, sudden swelling of one or both legs, heart or kidney failure occur, you should immediately consult a doctor. If severe symptoms of venous insufficiency (swelling, skin discoloration, feeling of tension and pain) suddenly appear, especially on one limb, it is necessary to exclude thrombosis of the veins of the lower extremities.
The use of the gel for varicose veins does not replace other preventive or therapeutic measures (e.g., wearing supportive elastic stockings, dousing with cold water).
Avoid contact with eyes and mucous membranes. Wash hands thoroughly after each application of the gel.
The gel contains methylparaben (E 218), which may cause an allergic reaction (including a delayed one), and in exceptional cases – bronchospasm, and propylene glycol (E 1520), which can cause skin irritation.
Due to the lack of relevant data, escuven gel should not be used during pregnancy and breastfeeding.
Does not affect.
There are no data on overdose.
Hypersensitivity reactions, including dermatitis, including allergic, skin rash, itching, erythema, burning sensation of the skin, bronchospasm, are possible. In case of such reactions, it is necessary to stop using the drug and consult a doctor.
Unknown. It is not recommended to use the gel on the same area of skin together with other topical agents.
Store in original packaging at a temperature not exceeding 25 °C. Keep out of reach of children. Shelf life – 3 years.
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