Posterisan suppositories are indicated for topical treatment of hemorrhoid symptoms.
Composition
1 suppository contains (active ingredient) 387.10 mg of standardized bacterial culture suspension (containing 6.6×10 8 E. coli killed and preserved in 6.6 mg of liquefied phenol).
Excipients: solid fat, polyethoxylated castor oil, hydrogenated.
Pharmacological properties
Pharmacodynamics
The drug stimulates local immune processes due to antigenic action, causing both nonspecific and specific immune reactions, resulting in increased local immune resistance. Accelerates and improves wound healing, has an anti-inflammatory effect, prevents reinfection and superinfection.
Pharmacokinetics
Due to sorption or transcytosis, components of the bacterial culture suspension act as antigens and initiate the process of local immunization, which, in turn, causes a protective immune response.
Contraindication
Hypersensitivity to the active substance or to any component of the drug.
Method of application
Before use, it is necessary to carry out hygienic procedures of the anal area. Apply rectally, adults one suppository 2 times a day (morning and evening), if possible after defecation.
The duration of treatment is determined by the doctor depending on the nature and course of the disease. Usually the duration of use is 5-7 days.
Application features
Pregnant women
There are no contraindications for the use of the drug during pregnancy and breastfeeding.
Children
Do not apply.
Overdose
No cases of overdose or intoxication have been reported. In case of accidental ingestion of the ointment (e.g. by children), gastrointestinal disorders (abdominal pain, nausea) are possible.
Side effects
In some cases, patients with hypersensitivity to the components of Posterisan suppositories may experience hypersensitivity reactions, including itching and burning. May cause contact dermatitis (e.g., due to hypersensitivity to phenol).
Storage conditions
Store in the original packaging at a temperature not exceeding 25 °C, in a dry place, out of the reach of children and protected from light.
Shelf life – 3 years.
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