Reparil Gel N tube 40 g

Composition

active ingredients: escin, diethylamine salicylate;

10 g of gel contains escin 100 mg (0.1 g) and diethylamine salicylate 500 mg (0.5 g);

Excipients: macrogol glyceryl caprylocaprate, disodium edetate, trometamol, carbomers, isopropyl alcohol, purified water, lavender oil, neroli oil. 

Release form

Gel.

Pharmacodynamics. Topical application of escin helps reduce the sensation of pain caused by sports injuries, such as sprains and dislocations.

In the case of increased vascular permeability caused by inflammatory processes, escin inhibits exudation, reducing the release of fluid from the vessels into the tissue and accelerates the reabsorption of existing edema. The mechanism of action is based on a change in the permeability of the capillary walls. In addition, escin increases capillary resistance, suppresses inflammatory processes and improves microcirculation.

Pharmacokinetics. Diethylamine salicylate has a pronounced analgesic effect. It freely penetrates the skin and has an analgesic effect deep in the affected area. The additional anti-inflammatory effect of diethylamine salicylate enhances the anti-inflammatory effect of escin and thus prevents the etiological factors of the disease.

Injuries due to blows, sprains, hematomas, bruises, tendinitis (inflammation of tendon tissues); pain syndrome in diseases of the spine (intervertebral disc herniation, osteochondrosis, lumbago, sciatica); phlebitis of superficial veins, varicose veins; treatment of local complications after intravenous injections or infusions.

Hypersensitivity to salicylates, escin or other components of the drug.

Unless otherwise prescribed by a doctor, adults and children over 12 years of age apply a thin layer of gel to the affected areas of the skin, spreading it evenly over the entire area, one to several times a day. The gel can be rubbed into the skin, but this is not necessary.

Children: The drug should not be prescribed to children under 12 years of age, as there is insufficient experience in this category of patients.

The gel should not be applied to open wounds, damaged skin, mucous membranes or areas of skin exposed to radiation. Avoid contact with the eyes. In case of sudden onset of severe symptoms of venous insufficiency (swelling, skin discoloration, feeling of tension and pain), especially in one limb, thrombosis of the veins of the lower extremities should be excluded.

There are no data available on the use of Reparil-gel N during pregnancy. No adequate experimental studies have been conducted on animals to study the reproductive toxicity of the components of Reparil-gel N. Therefore, the use of Reparil-gel N during pregnancy is not recommended, in particular, application to large areas of skin should be avoided. It is not known whether the components of Reparil-gel N enter breast milk. There are no data on experimental studies on animals on the passage of the components of the drug into breast milk. Therefore, the use of Reparil-gel N during breastfeeding is not recommended, in particular, application to areas of the mammary glands should be avoided.

Does not affect the ability to drive vehicles and other mechanisms.

No cases of overdose have been reported.

Criteria for assessing the frequency of adverse drug reactions:

very common (1/10), common (1/100 – 1/10), uncommon (1/1000 – 1/100), rare (1/10,000 – 1/1000), very rare (1/10,000), unknown (frequency cannot be estimated).

Very rarely, hypersensitivity reactions are possible, including contact dermatitis, skin rashes, itching, as well as changes at the site of application of the drug, including irritation, redness of the skin.

Not detected.

At a temperature not exceeding 25 °C. Do not freeze.