Duac Gel, 15 g tube

Indications

Duac Gel is used for the topical treatment of mild to moderate acne (acne vulgaris), mainly inflammatory lesions, in adults and children over 12 years old.

Composition

1 g of gel contains (active substances):

• Benzoyl peroxide anhydrous (as benzoyl peroxide aqueous) – 50 mg
• Clindamycin (as clindamycin phosphate) – 10 mg

Excipients: carbomer, dimethicone, sodium laurylsulfosuccinate, disodium edetate, glycerin, colloidal silicon dioxide (aqua), poloxamer, sodium hydroxide, purified water.

Contraindications

• Hypersensitivity to any component of the product or lincomycin
• Local enteritis, ulcerative colitis, or antibiotic-associated colitis (including pseudomembranous colitis), or history of these conditions
• Children under 12 years old

Method of Administration

For external use only. Adults and children over 12 years:

• Apply once daily in the evening to affected areas after thorough cleansing and drying.
• Wash hands after application.
• Moisturizer may be used if needed.
• If excessive dryness or peeling occurs, reduce frequency or temporarily stop treatment.
• Do not use more than once daily; more gel does not increase effectiveness.

Therapeutic effect may appear after 2–5 weeks. Maximum treatment duration: 12 weeks.

Special Considerations

Pregnancy: Use only if the expected benefit outweighs potential risk.

Breastfeeding: Use only if expected benefit outweighs risk. Avoid breast area application.

Drivers: No negative effects expected.

Overdose

Excessive topical application may cause severe skin irritation. Discontinue and allow recovery. Accidental ingestion may cause gastrointestinal side effects similar to systemic clindamycin.

Side Effects

• Very common: redness, peeling, dryness (usually mild to moderate)
• Common: burning sensation

Storage

Store in refrigerator (2–8 °C), out of reach of children. Do not freeze. After opening, keep below 25 °C, out of reach of children.

Shelf life: 1.5 years (after opening – 2 months).