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Albendazole 400 mg chewable tablets treat intestinal and systemic helminth infections; taken with food, dosage varies by condition and severity.
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Albendazole chewable tablets 400 mg blister 3 pcs
$15.51
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to: Australia, Canada, Czechia, Denmark, Estonia, Ireland, Israel, Italy, Japan, Lithuania, Mexico, Netherlands, Poland, Slovakia, South Korea, Switzerland, United Kingdom, United States and more
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Albendazole tablets are used for the indications listed below.
Intestinal forms of helminthiasis and cutaneous Larva Migrans syndrome (short-term treatment with low doses): enterobiasis, hookworm and necatoriasis, hymenolepidosis, teniasis, strongyloidiasis, ascariasis, trichocephalosis, clonorchiasis, opisthorchiasis, giardiasis in children.
Systemic helminth infections (long-term treatment with high doses):
- Cystic echinococcosis (caused by Echinococcus granulosus):
- if surgical intervention is not possible;
- before surgery;
- after surgery, if preoperative treatment was short, if helminths are present or live forms are found during surgery;
- after percutaneous cyst drainage for diagnostic or therapeutic purposes;
- Alveolar echinococcosis (caused by Echinococcus multiocularis):
- in inoperable disease, particularly in cases of local or distant metastases;
- after palliative surgery;
- after radical surgery or liver transplantation;
- Neurocysticercosis (caused by Taenia solium larvae):
- in the presence of single or multiple cysts or granulomatous brain lesions;
- with arachnoid or intraventricular cysts;
- with racemose cysts;
- Capillarosis (caused by Capillaria philippinensis), gnathostomiasis (caused by Gnathostoma spinigerum and related species), trichinosis (caused by Trichinella spiralis and T.pseudospiralis), toxocariasis (caused by Toxocara canis and related species).
Composition
Active ingredient: albendazole;
1 chewable tablet contains 400 mg of albendazole;
Excipients: corn starch, microcrystalline cellulose, sodium starch glycolate, colloidal anhydrous silicon dioxide, orange flavor, aspartame, talc, magnesium stearate.
Contraindication
- Hypersensitivity to albendazole, other benzylidazole derivatives, or other components of the drug.
- Retinal disease.
- A period lasting one menstrual cycle before a planned pregnancy.
- Phenylketonuria.
Method of application
The drug is taken with food. It is advisable to use it at the same time of day. If recovery does not occur after three weeks, a second course of treatment is prescribed.
The tablet can be chewed or crushed and taken with a small amount of water.
Application features
Pregnant women
The drug is contraindicated during pregnancy or breastfeeding and for the treatment of women planning to become pregnant.
Children
The drug is contraindicated for the treatment of children under 3 years of age in this dosage form.
Drivers
Given the presence of such a side effect as dizziness, it is recommended to refrain from driving or operating other mechanisms during the period of use of albendazole.
Overdose
Symptoms: nausea, vomiting, diarrhea, tachycardia, drowsiness, visual disturbances, visual hallucinations, speech disorders, loss of consciousness, liver enlargement, increased transaminase levels, jaundice; respiratory distress, brown-red or orange discoloration of the skin, urine, sweat, saliva, tears and feces in proportion to the dose of the drug.
Treatment: gastric lavage and symptomatic and supportive therapy are used.
Side effects
- From the digestive tract and liver: stomatitis, dry mouth, heartburn, nausea, vomiting, abdominal pain, flatulence, diarrhea, constipation.
- Hepatobiliary disorders: transient increase in liver enzyme activity, jaundice, hepatitis, hepatocellular damage.
- From the cardiovascular system: increased blood pressure, tachycardia.
- From the side of the central nervous system and peripheral nervous system: insomnia or drowsiness, headache, dizziness, confusion, disorientation, hallucinations, seizures, decreased visual acuity.
- Blood and lymphatic system disorders: leukopenia, neutropenia, thrombocytopenia, anemia, including aplastic anemia, agranulocytosis, pancytopenia. Patients with liver disease, including hepatic echinococcosis, are more susceptible to bone marrow suppression.
- Skin and subcutaneous tissue disorders: skin rash, hyperemia, erythema multiforme, Stevens-Johnson syndrome, alopecia inversa, pruritus, urticaria, pemphigus, dermatitis, edema.
- Renal and urinary disorders: renal dysfunction, acute renal failure, proteinuria.
- General disorders: bone pain, sore throat, fever, weakness.
Interaction
When using albendazole with theophylline, it is necessary to monitor the level of theophylline in the blood.
The systemic effect is increased if the drug is taken with food.
Grapefruit juice also increases the plasma levels of albendazole sulfoxide.
Due to possible disruption of P450 activity, there is a theoretical risk of interaction with the following drugs: oral contraceptives, anticoagulants, oral hypoglycemic agents, theophylline.
Storage conditions
Store in the original packaging at a temperature not exceeding 25ºС.
Keep out of reach of children.
Shelf life – 3 years.
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