Tobiflamin eye drops suspension bottle with dropper 5 ml

1 ml of suspension contains (active ingredients):

• tobramycin – 3.0 mg;
• dexamethasone – 1.0 mg;

Excipients: benzalkonium chloride, disodium edetate, sodium chloride, sodium sulfate anhydrous, tyloxapol, hydroxyethylcellulose, sulfuric acid and/or sodium hydroxide, water for injections.

• hypersensitivity to the active substances or to any component of the medicinal product;
• keratitis caused by the herpes simplex virus;
• cowpox, chickenpox and other viral infections of the cornea and conjunctiva;
• fungal diseases of the eye structures or treated parasitic eye infections;
• mycobacterial infections of the eye.

For ophthalmic use.

Adults, including elderly patients, and children from 12 to 18 years of age

One or two drops should be instilled into the conjunctival sac(s) every 4-6 hours. During the first 24-48 hours, the dose may be increased to one or two drops every 2 hours. The frequency of application of the drug should be gradually reduced as clinical signs improve.

You should be careful and not stop therapy prematurely.

In severe cases, instill one or two drops every hour until the inflammation is controlled, and gradually reduce the frequency of application to one or two drops every 2 hours for 3 days; then instill 1-2 drops every 4 hours for 5-8 days, and finally 1-2 drops daily for the last 5-8 days if necessary.

After cataract surgery, the dose is one drop 4 times a day, starting on the day of surgery and continuing for 24 days. Treatment can be started the day before surgery with one drop 4 times a day, continuing with one drop after surgery, and then 4 times a day for 23 days. If necessary, the frequency of use of the drug can be increased to one drop every 2 hours during the first two days of therapy.

It is recommended to constantly monitor intraocular pressure.

It is recommended to press on the nasolacrimal opening and gently close the eyelids after instillation. This reduces the systemic absorption of drugs administered into the eye, which reduces the likelihood of systemic side effects.

Use in children

The data obtained confirm the safety and effectiveness of the drug in children from 1 year of age, who were treated with the drug for 7 days for the treatment of superficial bacterial eye inflammation.

It can be used in children who need cataract surgery.

Method of use

The bottle should be shaken well before use.

To prevent contamination of the dropper tip and contents of the bottle, care should be taken not to touch the eyelids, surrounding areas, or other surfaces with the tip of the dropper bottle.

Store the bottle in an upright position.

Pregnant women

The use of the drug “Tobiflamin” during pregnancy is not recommended.

Because many drugs are excreted in human milk, consideration should be given to temporarily discontinuing breastfeeding while using this drug.

Drivers

This medicine has no or negligible influence on the ability to drive or use machines. Temporary blurred vision or other visual disturbances may affect the ability to drive or use machines. If blurred vision occurs during instillation, the patient should wait until the vision clears before driving or using machines.

Given the characteristics of this medicinal product, intended for topical use, no toxic effect is expected either when used in ophthalmology at the recommended doses or in the event of accidental ingestion of the contents of the vial. Possible clinical signs and symptoms of overdose with the drug (punctate keratitis, erythema, increased lacrimation, eyelid edema and itching) may be similar to the side effects observed in some patients.

In case of overdose with the drug “Tobiflamin” when applied topically, wash the excess drug from the eye(s) with warm water.

The most common adverse reactions, occurring in less than 1% of patients, were eye pain, increased intraocular pressure, eye irritation, and eye itching.

Store in the original packaging at a temperature not exceeding 25 °C, out of the reach of children.

Shelf life – 2 years.

After opening the bottle, the shelf life is no more than 4 weeks.