Alerzin film-coated tablets 5 mg 14 pcs

“Alerzin” tablets are used for the symptomatic treatment of allergic rhinitis (including perennial allergic rhinitis) and urticaria.

Composition

The active substance is levocetirizine dihydrochloride (one tablet contains 5 mg of levocetirizine dihydrochloride, which corresponds to 4.21 mg of levocetirizine).

Excipients: microcrystalline silicon cellulose, low-substituted hydroxypropyl cellulose, lactose, magnesium stearate; shell composition: Opadry II 33G28523 white (hypromellose, titanium dioxide (E 171), macrogol 3350, triacetylglycerol, lactose).

Contraindications

• Hypersensitivity to levocetirizine, cetirizine, hydroxyzine, to any other piperazine derivatives or to any other excipient of the drug;
• severe chronic renal failure (creatinine clearance <10 ml / minute);
• rare hereditary diseases of galactose intolerance, lactase deficiency or impaired absorption of glucose and galactose.

Method of administration

The drug is prescribed to adults and children over 6 years of age.

Recommended doses:

• adults and children over 12 years of age – the daily dose is 5 mg (one tablet) 1 time per day;
  children aged 6 to 12 years – the recommended daily dose is 5 mg (one tablet).
• For children from 2 to 6 years of age, it is impossible to adjust the dose of the drug in the dosage form of tablets.

Method of use:

take the tablet orally, regardless of the meal. The tablet should be swallowed whole, washed down with a small amount of water. It is recommended to use the daily dose in one dose.

Duration of use

Patients with intermittent allergic rhinitis (duration of symptoms of the disease is less than 4 days per week or for less than 4 weeks per year) should be treated according to the disease and history; treatment can be stopped if the symptoms disappear, and can be resumed again if the symptoms reappear. In case of persistent allergic rhinitis (duration of symptoms of the disease is more than 4 days per week and for more than 4 weeks per year) during the period of contact with allergens, the patient may be offered continuous therapy. There is clinical experience with the use of levocetirizine for a treatment period of at least 6 months.

In chronic diseases (chronic allergic rhinitis, chronic urticaria) the duration of treatment is up to one year (data are available from clinical studies using cetirizine (racemate)).

Features of use

Pregnant women

Levocetirizine is contraindicated during pregnancy. Levocetirizine passes into breast milk, so if necessary, breastfeeding should be discontinued. There are no clinical data (including animal studies) on the effect of levocetirizine on fertility.

Children

The drug in tablet form should not be used in children under 6 years of age, since this dosage form does not allow for the necessary correction of the dosage regimen. It is recommended that levocetirizine be used in a dosage form suitable for use in pediatrics in this category of patients.

Drivers

You should refrain from driving or operating machinery during treatment.

Overdose

Symptoms

Symptoms of overdose may include drowsiness in adults and initial agitation and increased irritability with subsequent drowsiness in children.

Treatment

There is no specific antidote to levocetirizine. In case of symptoms of overdose, symptomatic and supportive therapy is recommended. The need for gastric lavage should be considered shortly after taking the drug. Hemodialysis is not effective in removing levocetirizine from the body.

Side effects

On the part of the nervous system: drowsiness, headache, increased fatigue, weakness, asthenia, cramps, paresthesia, dizziness, fainting, tremor, dysgeusia.

On the part of the psyche: sleep disorders, agitation, hallucinations, depression, aggression, insomnia, suicidal thoughts, bad dreams.

On the part of the heart: increased heartbeat, tachycardia.

On the part of the organs of vision: visual impairment, blurred vision, oculogyration.

On the part of the organs of hearing and balance: vertigo.

On the part of the liver and biliary tract: hepatitis.

On the part of the kidneys and urinary system: dysuria, urinary retention.

On the part of the immune system: hypersensitivity, including anaphylaxis.

Respiratory, thoracic and mediastinal disorders: dyspnea.

Gastrointestinal disorders: diarrhea, vomiting, constipation, dry mouth, nausea, abdominal pain.

Skin and subcutaneous tissue disorders: angioedema, persistent drug eruptions, pruritus, rash, urticaria.

Musculoskeletal, connective tissue and bone disorders: muscle pain, joint pain.

Nutritional and metabolic disorders: increased appetite.

Pruritus has been reported after discontinuation of levocetirizine.

Storage conditions:

Store in the original packaging at a temperature not exceeding 30 °C, out of the reach of children.