Composition and form of release
Composition of Afletin
Active ingredient: simethicone;
1 capsule contains simethicone 125 mg;
excipients: gelatin, glycerin.
Release form
Soft capsules.
Pharmacological properties
Pharmacodynamics.
Simethicone, which is part of the drug, is a non-toxic inert surfactant made on the basis of silicon, an antifoam. It changes the surface tension of gas bubbles formed in the intestine and causes their destruction. The gases released in this case can be either absorbed by the intestinal walls or excreted from the body due to intestinal peristalsis. The use of simethicone before the start of diagnostic studies of the abdominal organs prevents the appearance of image defects caused by gas bubbles; promotes thorough irrigation of the colon mucosa with a contrast agent, which prevents rupture of the contrast film even in the case of intestinal distension.
Pharmacokinetics.
Simethicone acts exclusively on the surface of gas bubbles and is not absorbed by the mucous membrane of the digestive tract. Simethicone is excreted unchanged after ingestion. Simethicone does not have a central effect.
Indication
Symptomatic treatment of gastrointestinal disorders associated with gas formation, such as flatulence, including in the postoperative period. as an aid in diagnostic examinations of the abdominal organs (x-ray, ultrasound) and in preparation for gastroduodenoscopy. as an antifoam in intoxications with surfactants (washing powders or other detergents).
Contraindication
Hypersensitivity to the drug and its components; intestinal obstruction; obstructive diseases of the digestive tract.
Method of administration and doses
The drug is administered orally to adults and children over 12 years of age. Taking the drug does not depend on food intake.
Symptomatic treatment of gastrointestinal disorders: 1 capsule 3 times a day.
As an aid in conducting diagnostic tests: 1 capsule 3 times a day the day before the test and another 1 capsule in the morning on the day of the test.
As an antifoam for intoxications with surfactants (washing powders or other detergents): dosage depends on the severity of intoxication.
The minimum recommended dose is 3 capsules.
The duration of treatment is determined individually. If necessary, the drug can be taken for a long time.
Children. The drug is used in children from 12 years of age. Children under 12 years of age are prescribed the drug in the form of liquid dosage forms.
Interaction
Levothyroxine may bind to simethicone. The absorption of levothyroxine in the intestine may be impaired when taken simultaneously with simethicone.
Application features
If complaints recur or if digestive tract complaints persist, you should consult a doctor.
Use during pregnancy or breastfeeding
There are no clinical data on the use of the drug Afletin in pregnant women. Since the active ingredient is not absorbed by the mucous membrane of the digestive tract, no effect of the drug on the fetus or accumulation of the drug in breast milk should be expected.
The use of the drug Afletin during pregnancy or breastfeeding is possible only when the expected benefit to the woman outweighs the potential risk to the fetus or child.
Drivers
Since simethicone is an inert substance that is not absorbed, the effect on driving or other mechanisms is practically excluded.
Overdose
To date, cases of overdose are unknown. Since simethicone is chemically and physiologically inert, intoxication is practically excluded. In case of using doses higher than recommended, you should consult a doctor.
Adverse reactions
On the part of the immune system: allergic manifestations, hypersensitivity reactions, including itching, rash, urticaria.
Storage conditions
Store in original packaging at a temperature not exceeding 25 °C. Keep out of reach of children. Shelf life – 2 years.
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