Decatylen Flu lozenges 8.75 mg 2 blisters of 12 pcs.

• active ingredient: flurbiprofen;
• 1 lollipop contains 8.75 mg of flurbiprofen;
• excipients: isomalt (E 953), maltitol (E 965), polyethylene glycol 300, peppermint oil, honey flavoring, lemon flavoring.

• Hypersensitivity to flurbiprofen or to any of the excipients of the drug.
• History of hypersensitivity reactions (e.g. bronchial asthma, bronchospasm, rhinitis, angioedema or urticaria) after taking acetylsalicylic acid or other non-steroidal anti-inflammatory drugs (NSAIDs).
• Recurrent peptic ulcer/bleeding in history or in the acute phase (two or more episodes confirmed by characteristic clinical manifestations) and intestinal ulcers.
• History of gastrointestinal bleeding or perforation, severe colitis, hemorrhagic or hematopoietic disorders related to previous NSAID therapy.
• The last trimester of pregnancy.
• Severe heart failure, severe kidney failure, or severe liver failure.

Hypersensitivity reactions to NSAIDs have been reported and may include: non-specific allergic reactions and anaphylaxis; airway reactivity, e.g. bronchial asthma, exacerbation of bronchial asthma, bronchospasm, dyspnoea; various skin reactions, e.g. pruritus, urticaria, angioedema, and rarely exfoliative and bullous dermatoses (including epidermal necrolysis and erythema multiforme).

Events such as oedema, hypertension and heart failure have been reported with the use of NSAIDs. Clinical trials and epidemiological data suggest that the use of some NSAIDs (particularly long-term and at high doses) is associated with a slightly increased risk of arterial thrombotic events (e.g. myocardial infarction or stroke). There is insufficient data to exclude such a risk with flurbiprofen 8.75 mg lozenges.

To minimize undesirable effects, the lowest effective dose should be used for the shortest period necessary to relieve symptoms. It is not recommended to use the drug for more than 3 days. Lozenges should be sucked until completely dissolved. When sucking, the lollipop should be moved throughout the oral cavity to prevent irritation of the mucous membrane at the site of sucking.

Adults and children 12 years of age and older should take 1 lozenge every 3–6 hours until pain is relieved. The maximum daily dose is 5 lozenges.

Use during pregnancy or breastfeeding

Flurbiprofen should not be used during the first two trimesters of pregnancy unless clearly necessary. If flurbiprofen is used by a woman attempting to conceive or during the first and second trimesters of pregnancy, the lowest possible dose should be used for the shortest duration possible.

Flurbiprofen is contraindicated during the third trimester of pregnancy.

In some studies, flurbiprofen has been found in breast milk at very low concentrations. It is unlikely that it will have any negative effects on the breastfed infant. However, due to the possible occurrence of adverse effects of NSAIDs in breastfed infants, the use of Decatylen Flu in breastfeeding women is not recommended.

Children

Do not use in children under 12 years of age.

Ability to influence reaction speed when driving vehicles or other mechanisms

Studies on the ability to influence the reaction rate when driving vehicles or other mechanisms have not been conducted.

Symptoms. In most patients, the use of clinically significant amounts of NSAIDs caused only nausea, vomiting, epigastric pain or, less commonly, diarrhea. Tinnitus, headache and gastrointestinal bleeding may also occur. In more severe poisoning, CNS toxicity may occur in the form of drowsiness, sometimes agitation, visual disturbances, disorientation or coma. Sometimes patients develop convulsions. In severe poisoning, metabolic acidosis and an increase in prothrombin time/INR (International Normalized Ratio) may occur, presumably due to interaction with circulating clotting factors. Acute renal failure and liver damage may occur. In patients with bronchial asthma, its course may be exacerbated.

Treatment. Treatment should be symptomatic and supportive, and include maintaining a patent airway and monitoring cardiac function and vital signs until the patient’s condition is normal. Activated charcoal or gastric lavage may be used and, if necessary, correction of serum electrolyte balance if less than 1 hour has passed since the administration of a potentially toxic dose of the drug. In case of frequent or prolonged seizures, treatment should be carried out with intravenous diazepam or lorazepam. In case of bronchial asthma, bronchodilators should be used. There is no specific antidote to flurbiprofen.

Store at a temperature not exceeding 30 ° C. Keep out of the reach of children.