Eucazolin Aqua nasal spray 1 mg/g bottle 10 ml

Active substance: chylometazoline;

1 g of spray contains 1 mg of xylometazoline hydrochloride in 100%;

excipients: benzalkonium chloride; eucalyptus oil; edetate disodium; propylene glycol; polyethylene glycol 1500; povidone; hypromellose; polysorbate 20; sodium hydrogen phosphate, dodecahydrate; potassium dihydrogen phosphate; the water is purified.

You can buy Evkazolin Aqua at an attractive price using the MIS Pharmacy 9-1-1 website.
Evkazolin Aqua nasal drops, price and instructions for Evkazolin Aqua drops are listed in the catalog of the MIS Pharmacy 9-1-1 website.

Nasal spray.

Main physico-chemical properties: when the drug leaves the bottle through a dosing pump with a nasal atomizer, it is sprayed in the form of an aerosol stream, which has a specific smell and is the liquid parts dispersed in the air.

Eukazolin Aqua can be bought using the MIS Pharmacy 9-1-1 website at an attractive price.
Evkazolin Aqua drops, price and Evkazolin Aqua nose drops, instructions are listed in the catalog of the MIS Pharmacy 9-1-1 site.

Means used in diseases of the nasal cavity. Anti-edematous and other drugs for local use in diseases of the nasal cavity. Sympathomimetics, simple drugs. ATX code R01A A07.

You can buy Evkazolin Aqua nasal spray using the MIS Pharmacy 9-1-1 website at an attractive price.
The price of Evkazolin Aqua and the instructions for use of Evkazolin Aqua are indicated in the catalog of the MIS Pharmacy website 9-1-1.

Pharmacodynamics
Xylometazoline is a sympathomimetic agent acting on α-adrenergic receptors.

Xylometazoline, when used nasally, leads to the narrowing of blood vessels of the nasal mucosa and adjacent areas of the nasopharynx, thereby eliminating swelling and hyperemia of the nasal and nasopharyngeal mucosa, and also reduces the associated increased secretion of mucus and relieves the product. cleaning the nasal passages and facilitating nasal breathing.

The effect of the drug begins within 2 minutes after application and lasts up to 12 hours (for example, all night).

The drug is well tolerated by patients with sensitive mucous membranes and does not reduce mucociliary function. Research results have shown that xylometazoline reduces the infectious activity of the human rhinovirus associated with the common cold.

Pharmacokinetics
With local application, xylometazoline is practically not absorbed, the concentration of xylometazoline in the plasma is so low that it is practically not detected (the concentration in the blood plasma is close to the detection limit).

Xylometazoline has no mutagenic properties. Also, no teratogenic effects of xylometazoline were found in animal studies.

You can buy Evkazolin Aqua nasal drops using the MIS Pharmacy 9-1-1 website at an attractive price.
The price of Evkazolin Aqua spray is indicated in the catalog of the MIS Pharmacy 9-1-1 website.

Symptomatic treatment of nasal congestion in SARS, hay fever, allergic rhinitis, sinusitis.

To facilitate the outflow of secretions in diseases of the paranasal sinuses.

Auxiliary therapy of otitis media (to reduce swelling of the mucous membrane of the nasal cavity).

During diagnostic interventions (rhinoscopy).

Evkazolin® Aqua, nasal spray, to be used by adults and children over 12 years old.

Adults and children over 12 years old:

1 injection in each nasal passage up to 3 times a day if necessary. Apply no more than 3 times per nasal passage per day. The duration of treatment depends on the course of the disease and should not exceed 10 days in a row.

The dosed spray ensures the accuracy of dosing and distribution of the solution on the surface of the nasal mucosa.

Before use, it is necessary to prepare the dosing device by making several injection movements until the spray is released into the air. With further use, the dosing device will be ready for immediate use.

It is necessary to apply the spray in the following way:

Thoroughly clean the nose before using the drug;

– hold the bottle vertically, supporting the bottom with your thumb and placing the tip between two fingers;

– tilt the bottle slightly and insert the tip into the nasal passage;

– inject and at the same time take a light breath through the nose;

– after use, before closing the tip with a cap, the tip should be cleaned and dried;

– in order to prevent infection, each bottle with the drug can be used by only one person.

The last application is recommended immediately before going to bed.

Children. The drug should not be used by children under 12 years of age.

Hypersensitivity to any of the components of the drug, acute coronary diseases, coronary asthma, hyperthyroidism, angle-closure glaucoma, transsphenoidal hypophysectomy, or a history of transnasal / transoral surgical interventions with exposure of the dura mater. concomitant treatment with MAO inhibitors and within 2 weeks after stopping their use.

Possible side effects: burning in the nose or throat, tingling, dryness in the nose, sneezing, nausea, shortness of breath, angioedema. in isolated cases, systemic allergic reactions are possible. with long-term use or frequent use of high concentrations, swelling of the nasal mucosa, manifestations of the resorptive effect in the form of dizziness, headache, insomnia, vomiting, increased appetite, palpitations, heart rhythm disorders, and short-term visual impairment may occur. with particularly long-term use of the drug in high doses, a depressive state may develop.

The drug should not be used continuously for a long period (more than 10 days in a row) in case of chronic rhinitis. long-term drug therapy can lead to the opposite effect. the recommended dose of the drug should not be exceeded, especially when treating children and elderly patients.

The drug should be prescribed with caution to patients who, when using adrenergic drugs, experience severe side effects, which are manifested in the form of insomnia, dizziness, tremors, cardiac arrhythmia, and increased blood pressure.

The drug should be prescribed with caution to patients with cardiovascular disease, hypertension, diabetes, thyroid disease, and difficulty urinating.

Due to the vasoconstrictor effect of the drug, an increase in intraocular pressure is possible.

The drug should be prescribed with caution to patients with cardiovascular diseases, arterial hypertension, diabetes patients, pheochromocytoma, hypertrophy of the prostate gland, and should not be used in patients receiving treatment with MAO inhibitors and within 2 weeks after stopping their use.

The drug contains benzalkonium chloride, which can cause irritation of the nasal mucosa.

Each package of drops or spray should be used by only one person to avoid infection.

The drug cannot be used during pregnancy due to a potential vasoconstrictor effect.

There is no evidence of any adverse effect on the infant. It is not known whether xylometazoline is excreted in breast milk, so caution is necessary, and the drug during breastfeeding should be used only as prescribed by a doctor.

fertility

There are no relevant data on the effect of the drug on fertility. Because systemic exposure to xylometazoline hydrochloride is very low, the potential for effects on fertility is extremely low.

Children. Eukazolin Aqua is used in children over 10 years of age.

The ability to influence the speed of reaction when driving a motor vehicle or working with other mechanisms. The drug does not affect the ability to drive vehicles and complex mechanisms when used in recommended doses, but the possibility of temporary visual impairment should be taken into account.

Eukazolin aqua interacts with other drugs only in the presence of a resorptive effect. adrenomimetic drugs of other groups enhance the effect of Eukasolin aqua. adrenolytics and sympatholytics, antagonists of calcium ions weaken its effect.

Simultaneous administration of MAO inhibitors or tricyclic antidepressants can lead to an increase in blood pressure due to the effect of these drugs on the cardiovascular system.

Excessive local application of xylometazoline hydrochloride or its accidental ingestion can lead to severe dizziness, sweating, significant lowering of body temperature, headache, bradycardia, arterial hypertension, respiratory depression, coma and convulsions. High blood pressure can change to low blood pressure. Younger children are more sensitive to toxicity than adults.

All patients with suspected overdose should be given appropriate supportive measures and, if necessary, immediate symptomatic treatment under control. Medical care should include observation of the patient for several hours. In case of severe overdose accompanied by cardiac arrest, resuscitation measures should last at least 1 hour.

2 years.

Do not use the drug after the expiration date indicated on the package.

In a place protected from light at a temperature not higher than 25 °C.