Noxsprey nasal spray 0.05% container 10 ml

Pharmacodynamics. Noxprey – an α-adrenomimetic, an imidazoline derivative, belongs to the group of local vasoconstrictors. narrows blood vessels at the site of application, reduces swelling of the mucous membrane of the nose and upper respiratory tract, reduces discharge from the nose. restores nasal breathing. elimination of swelling of the nasal mucosa helps to restore the aeration of the paranasal sinuses, the middle ear cavity, which prevents the development of bacterial complications. Oxymetazoline has antiviral, anti-inflammatory, immunomodulatory and antioxidant effects. thanks to this combined mechanism of action, a quick and effective elimination of the symptoms of acute rhinitis (nasal congestion, rhinorrhea, sneezing, poor health) was observed. with local nasal application in therapeutic concentrations, it does not irritate the mucous membrane of the nose, does not cause hyperemia. essential oils, included in the composition of the drug, contribute to the elimination of the feeling of irritation of the nasal mucosa, protect it from excessive drying.

Pharmacokinetics. Was not studied.

Acute respiratory diseases accompanied by nasal congestion. acute rhinitis allergic rhinitis. vasomotor rhinitis. to restore drainage and nasal breathing in diseases of paranasal sinuses, eustachianitis. to eliminate swelling before diagnostic manipulations in the nasal passages.

Noxprey, Noxprey active. adults and children older than 6 years use 1 injection in each nostril 2-3 times a day. doses higher than recommended should be used only under the supervision of a doctor. use the drug for no more than 5-7 days. the drug can be used again only after a few days.

Nokspray Maluk is intended for use in the nose. Babies under 4 weeks of age use 1 drop in each nostril 2-3 times a day. Children aged 5 weeks to 1 year are prescribed 1-2 drops in each nostril 2-3 times a day for 5-7 days.

Nokspray Children’s. Children aged 1 to 6 years – 1 injection in each nostril 2-3 times a day. Doses higher than recommended should be used only under the supervision of a doctor. The drug should not be used for more than 5-7 days. The drug can be used again only after a few days.

Children. Noxspray Baby is used for children under 1 year of age. Children’s Noxspray should be prescribed to children aged 1 to 6 years. Noxprey and Noxprey Aktiv are used for children over 6 years old.

Hypersensitivity to the components of the drug, atrophic rhinitis, when using MAO inhibitors and within 2 weeks after stopping treatment with MAO inhibitors, as well as other drugs that contribute to the increase of hell, with increased intraocular pressure, especially with angle-closure glaucoma, with severe forms of cardiovascular diseases (for example, coronary heart disease, ag), pheochromocytoma, metabolic disorders (hyperthyroidism, diabetes, porphyria), hypertrophy of the prostate gland.

On the part of the respiratory system: discomfort in the nose, burning or dryness of the nasal mucosa, a feeling of severe congestion in the nose (reactive hyperemia), sneezing, nosebleeds, apnea in newborns and young children, especially in case of overdose.

From the nervous system: headache, drowsiness, fatigue, lethargy, insomnia, anxiety, convulsions, hallucinations, dizziness, nausea, vomiting.

From the side of the cardiovascular system: local nasal application of the drug can cause systemic effects (sensation of interruptions in the work of the heart, tachycardia, arterial hypertension).

From the side of the immune system: allergic reactions may occur, including rash, itching, angioedema.

Insert the tip of the bottle nozzle into each nostril and sharply press 1 time on the bottle. during air injection, draw in through the nose. you should not tilt your head back and turn the vial over when injecting the drug (the vial is held strictly vertically). to prevent the spread of infection, one bottle should not be used by several people.

It is necessary to avoid long-term use and overdose of the drug. Long-term use of a nasal decongestant can weaken the effect of the drug. Abuse of this agent can cause atrophic rhinitis, mucosal atrophy, and reactive hyperemia with drug-induced rhinitis. After using the drug, special observation of patients with chronic rhinitis is necessary, and in case of elimination of edema before diagnostic manipulations. Doses higher than recommended should be used only under the supervision of a doctor. The duration of continuous use of the drug should not exceed 7 days.

Use during pregnancy or breastfeeding. The use of the drug is possible with special caution in the case when, in the opinion of the doctor, the expected benefit for the mother exceeds the potential risk for the fetus / child. Do not exceed the recommended dose.

The ability to influence the speed of reaction when driving a motor vehicle or working with other mechanisms. After long-term use of the drug in doses exceeding the recommended, general effects on the cardiovascular system cannot be excluded. In such cases, the ability to drive a vehicle may decrease.

The drug should not be used simultaneously with other local vasoconstrictors and means for intranasal use (the frequency of adverse reactions increases), with MAO inhibitors and other drugs that contribute to the increase of hell due to the risk of ag.

With a significant overdose or with accidental ingestion, the following symptoms may occur: mydriasis or miosis, nausea, vomiting, cyanosis, pallor, increased sweating, hyperthermia, spasms, tachycardia, a feeling of interruptions in the work of the heart, arrhythmia, cardiovascular insufficiency, ag, respiratory disorders, pulmonary edema, cardiac arrest, hyposmia, agitation, convulsions, mental disorders. in addition, it is possible to suppress the functions of the central nervous system, which is accompanied by drowsiness, a decrease in body temperature, bradycardia, arterial hypotension, apnea and the possible development of coma.

Therapeutic measures in case of overdose: gastric lavage, taking activated charcoal, mechanical ventilation if necessary. In case of hypertension, vasodilators (phentolamine, sodium nitroprusside) should be used. Vasopressors should not be used. If necessary, benzodiazepines should be prescribed in case of violation, anticonvulsant therapy should be carried out with benzodiazepines and/or barbiturates.

Noxspray, Noxspray active, Noxspray for children – at a temperature not higher than 30 °C.

Noxspray Baby – at a temperature not higher than 25 °C.