Pimafucin is an antifungal agent. The active substance of the drug is natamycin, a macrolide antibiotic of the polyene series. It has a broad spectrum of action. It exhibits fungicidal activity, since it blocks the sterols of the cell membranes of fungi, which leads to the death of the microorganism. It is sensitive to fungi of the genus Candida spp. It exhibits somewhat less sensitivity to dermatophytes. To date, no cases of resistance to natamycin have been observed in clinical practice.