Amizon film-coated tablets 0.25 g 40 pcs.

• 1 tablet contains Amizon (enisamium iodide) 250 mg (0.25 g);
• excipients: lactose monohydrate, microcrystalline cellulose, povidone, croscarmellose sodium, calcium stearate;
• shell: OPADRY II Clear 85F19250 (polyethylene glycol, polysorbate 80, polyvinyl alcohol, talc).

Hypersensitivity to drugs containing iodide, molecular iodine or covalently bound iodine, as well as to other components of the drug.

Enisamium iodide tablets are swallowed without chewing 2 hours before meals.

The maximum single dose is 1000 mg (1 g), the maximum daily dose is 2000 mg (2 g).

Treatment.

Adults are prescribed enisamium iodide at a dose of 500 mg (0.5 g) 3 times or 1000 mg (1 g) 2 times a day.

Children over 12 years of age are prescribed enisamium iodide at a dose of 500 mg (0.5 g) 3 times a day.

Children aged 6 to 12 years are prescribed 125 mg (0.125 g) 2–3 times a day.

Duration of treatment is 7 days.

Prevention. Adults and children over 16 years old – 250 mg (0.25 g) per day for 3-5 days, then 250 mg (0.25 g) once every 2-3 days for 2-3 weeks; children 6-12 years old – 125 mg (0.125 g) every other day for 2-3 weeks; children 12 to 16 years old – 250 mg (0.25 g) every other day for 2-3 weeks.

Enisamium iodide administration leads to an increase in plasma iodide levels. The secondary increase in circulating iodide levels triggers a self-regulation mechanism of thyroid function, in which the uptake of inorganic iodide by thyrocytes is inhibited, which helps prevent excessive thyroid hormone production; at the same time, the level of thyroid-stimulating hormone increases transiently (Wolf-Chaikoff phenomenon). This effect lasts for several days; after discontinuation of treatment, thyroid function returns to normal. In some cases, a transient increase in thyroid-stimulating hormone has been observed for several weeks.

Pregnant women

The drug is contraindicated for use during pregnancy, as clinical studies of enisamium iodide have not been conducted in pregnant women.

Children

The drug in this dosage form should not be used in children under 6 years of age.

Drivers

Taking Amizon does not affect the ability to drive or operate other mechanisms.

No reports of overdose with Amizon have been received in clinical trials or during post-marketing use.

There is no specific antidote.

Infections and invasions: folliculitis, nasopharyngitis, rhinitis.

Respiratory, thoracic and mediastinal disorders: dyspnea.

Blood and lymphatic system disorders: lymphadenopathy.

Nervous system disorders: headache, dizziness.

Visual disorders: eyelid edema.

Store in a place protected from light at a temperature not exceeding 25°C.

Keep out of reach of children.