Dexamethasone tablets 0.5 mg blister 10 pcs.

Active ingredient: dexamethasone;

1 tablet contains 0.5 mg of dexamethasone;

Excipients: lactose, pregelatinized starch, magnesium stearate, colloidal silicon dioxide.

Hypersensitivity to dexamethasone or any other ingredient of the drug. Acute viral, bacterial or systemic fungal infections (if appropriate therapy is not used), Cushing’s syndrome, vaccination with a live vaccine, and breastfeeding (except in urgent cases).

The dose should be determined individually according to the specific patient’s disease, the intended period of treatment, tolerability of corticosteroids, and the body’s response.

Pregnant women

Dexamethasone should be administered to pregnant women only in rare urgent cases when the expected benefit to the mother outweighs the potential risk to the fetus.

Children

Use in children from birth only if absolutely necessary.

Drivers

Dexamethasone does not affect the ability to drive a car or use other mechanisms.

There have been isolated reports of acute overdose or death due to acute overdose.

A single intake of an excessive number of tablets usually does not lead to clinically significant intoxication.

Overdose, usually only after several weeks of excessive doses, is manifested by symptoms of increased side effects described, in particular: primarily Cushing’s syndrome, acne, ecchymoses, hirsutism, nausea, anorexia, peptic ulcer disease, joint pain, myopathy, myalgia, shortness of breath, dizziness, loss of consciousness, fever, increased blood pressure, hyperlipidemia, osteoporosis, orthostatic hypotension, development of infections, steroid diabetes, “moon-shaped” face, sexual dysfunction.

Treatment. The dose of the drug should be reduced or the drug should be discontinued, further treatment is symptomatic. There is no specific antidote. Hemodialysis is not an effective method of accelerating the removal of dexamethasone from the body.

The most common adverse reactions of short-term treatment are transient adrenal insufficiency, glucose intolerance, increased appetite and weight gain, and mental disorders; more rare adverse effects are allergic reactions, hypertriglyceridemia, gastric and duodenal ulcers, and acute pancreatitis.

Concomitant use of nonsteroidal anti-inflammatory drugs or ethanol with dexamethasone increases the risk of gastrointestinal bleeding and ulceration.

The efficacy of dexamethasone is reduced when rifampicin, carbamazepine, phenobarbital, phenytoin, primidone, ephedrine, or aminoglutethimide are administered concomitantly, and the dose of dexamethasone should be increased in such combinations. Interactions between dexamethasone and all of the above drugs may distort the dexamethasone suppression test. This should be taken into account when interpreting the test results.

Store in the original packaging to protect from light and moisture.

The medicinal product does not require special temperature storage conditions.

Keep out of reach of children.

Shelf life – 2 years.