Persen film-coated tablets 40 pcs

Pharmacodynamics. Persen, Persen Forte are herbal preparations with a mild sedative effect.

The combination of substances exhibits a weak sedative effect and is indicated for the elimination of mild transient nervous tension (as a daily sedative for mental stress, excitement, irritability).

Valerian has a sedative effect. It has a positive effect on well-being with symptoms of irritability, such as restlessness, excitement and tension due to nervous overload. In case of insomnia, it helps to fall asleep faster. Melissa also has a sedative and antispasmodic effect.

Peppermint is traditionally used in combination with valerian in sedative preparations.

Persen, Persen forte are used for neuroses when taking strong sedatives is inappropriate. Indications for use are determined solely on the basis of long-term experience.

Persen Cardio is a herbal preparation with a mild sedative effect.

The drug contains dry extracts of passionflower herb and hawthorn leaves and flowers.

Preparations containing passionflower herb are used for temporary mental overload, agitation, and insomnia.

Hawthorn leaf and flower extract increases cardiac conduction, improves coronary blood flow and vascular circulation, prevents cardiac arrhythmia and moderately lowers blood pressure.

The effectiveness of the combination of these plants is based on their traditional use. The effects of the medicinal plants complement each other. The combination exhibits moderate sedative and cardiotonic activity.

Persen Night. Valerian root and passionflower have a calming effect on minor anxiety and tension caused by moderate stress, and also make it easier to fall asleep.

Pharmacokinetics: No data available.

Persen, Persen Forte are prescribed for neuroses accompanied by the following symptoms:

• jitters;
• concern;
• tension caused by stress;
• sleep disorders.

Persen Cardio: temporary mild forms of mental tension, anxiety and excitability. Functional disorders of the heart and circulatory system associated with stress (for example, a feeling of increased heartbeat).

Persen Night is prescribed as a sleeping pill.

Persen. adults and children over 12 years of age: with mental stress, excitement or irritability, it is recommended to use 3 tablets 3 times a day; with insomnia – 3 tablets 1 hour before bedtime.

The tablets should be swallowed whole with water, regardless of meals.

Persen Forte. Adults and children over 12 years of age: for mental stress, excitement or irritability, it is recommended to use 2 capsules 2 times a day; for insomnia – 2 capsules 1 hour before bedtime.

The capsules should be swallowed whole with water, regardless of meals.

The drug is characterized by a gradual onset of action. To achieve the optimal treatment effect, it is recommended to use it for at least 14 days.

The duration of treatment is not limited. Even with prolonged use of the drug, addiction is not observed. There is no withdrawal syndrome after discontinuation of treatment.

If there is no improvement in the condition 14 days after the start of treatment, you should consult a doctor.

Persen Cardio. Adults and children over 12 years of age. Recommended dose – 1 capsule per day. If necessary, the dose can be increased to 1 capsule 2 times a day. Maximum daily dose – 2 capsules.

Capsules should be taken before meals (1 hour), with water.

To achieve optimal therapeutic effect, the drug should be taken for at least 6 weeks. If after 6 weeks of treatment the patient’s condition worsens or does not improve, you should consult a doctor.

Persen Night. Adults and children over 12 years of age: 1 capsule 30 minutes before bedtime.

Swallow the capsules whole with water, regardless of food intake.

The drug Persen Night is characterized by a gradual onset of action. To achieve the optimal effect of treatment, it is recommended to use the drug continuously for at least 2 weeks. The duration of treatment is not limited. Even with prolonged use of the drug Persen Night, addiction is not observed. There is no withdrawal syndrome after discontinuation of treatment.

If no improvement is noted within 14 days of starting treatment, you should consult a doctor.

Hypersensitivity to valerian, lemon balm, peppermint, passionflower, hawthorn or other components of the drug. Severe arterial hypotension, bradycardia, etc. Depression or other conditions accompanied by suppression of the central nervous system.

Gastrointestinal tract: frequency cannot be estimated – nausea, cramps; possible exacerbation of heartburn.

Very rarely, drowsiness, asthenic manifestations (weakness, decreased mood and performance, suppression of emotional reactions), dizziness, depression are noted. If other side effects occur (for example, hypersensitivity reactions, including rash, itching, urticaria, redness and swelling of the skin), you should consult a doctor.

In patients with severe liver dysfunction or a history of severe liver disease, the drug should be used with caution.

Patients with gastroesophageal reflux (heartburn) should avoid using preparations containing peppermint leaves, as it may worsen their condition.

Patients with gallstone disease or other diseases of the bile ducts and gallbladder should be given medications containing peppermint leaves with extreme caution.

The drug contains lactose, so it should not be used in patients with rare hereditary problems of galactose intolerance, the Lapp lactase deficiency or glucose-galactose malabsorption.

1 tablet contains 14 mg of glucose and 67 mg of sucrose, 1 capsule contains 35 g of glucose, therefore the drug should not be prescribed to patients with rare hereditary forms of fructose intolerance, sucrase-isomaltase deficiency or glucose-galactose malabsorption syndrome.

While using the drug, you should refrain from drinking alcoholic beverages.

Use during pregnancy and breastfeeding. The efficacy and safety of use during pregnancy and breastfeeding have not been established, therefore it is not recommended to use the drug during this period.

Children: There are no data on the use of the drug in children under 12 years of age, therefore its use in this category of patients is not recommended.

Ability to influence the reaction rate when driving vehicles or working with other mechanisms. The drug may affect the ability to drive vehicles and mechanisms, therefore, during its use, it is recommended to refrain from driving vehicles or other mechanisms until individual sensitivity is determined.

Data on interactions with other drugs are limited. Before using the drug simultaneously with other drugs, you should consult a doctor.

No clinically significant interactions with active substances metabolized by CYP 2D6, CYP 3A4/5, CYP 1A2 or CYP 2E1 have been identified.

Concomitant use with synthetic sedatives (benzodiazepines) without consulting a doctor is not recommended.

With simultaneous use, the effects of other sedatives and hypnotics, antispasmodics, analgesics, anxiolytics, and alcohol may be enhanced.

Symptoms. A dose of about 20 g of valerian roots, which is equivalent to approximately 103 tablets of Persen and 42 capsules of Persen Forte, can cause such minor symptoms as fatigue, cramps, a feeling of tightness in the chest, dizziness, hand tremors, dilated pupils. These symptoms disappear within 24 hours. Overdose of drugs containing valerian can also cause headache, drowsiness, lethargy, general weakness, abdominal pain, nausea, decreased hearing and vision, bradycardia / tachycardia, decreased concentration, increased sedative effect.

There are no reports of overdoses of lemon balm and peppermint leaves.

Treatment is symptomatic (gastric lavage, administration of activated charcoal).

Persen: at a temperature not exceeding 25 °C; Persen Forte, Persen Cardio, Persen Night: at a temperature not exceeding 25 °C in the original packaging. Keep out of the reach of children.