Piascledine 300 is a nonsteroidal anti-inflammatory and antirheumatic agent.
Piascledine 300 is used in rheumatology for the treatment of adults: symptomatic treatment of osteoarthritis of the knee joints.
Composition
active ingredients: avocado oil unsaponifiables; soybean oil unsaponifiables;
1 capsule contains a mixture of avocado and soybean oils unsaponifiables 300 mg, which corresponds to avocado oil unsaponifiables 100 mg, soybean oil unsaponifiables 200 mg;
excipients: colloidal anhydrous silicon dioxide, butylhydroxytoluene (E 321), polysorbate 80;
capsule shell: gelatin, titanium dioxide (E 171).
Contraindications
Allergy to any of the active or auxiliary ingredients of the drug.
Side effects
The most common side effects with Piascledine 300 are diarrhoea, abdominal pain, upper abdominal discomfort and nausea.
The following effects have also been reported:
Common (may affect up to 1 in 10 people): diarrhoea.
Uncommon (may affect up to 1 in 100 people): allergic reactions such as itching, rash, redness, hives and eczema; headache; upper abdominal discomfort, heartburn, nausea, bad taste in the mouth, abdominal pain, change in stool colour; dark urine; weakness, tiredness.
Rare (may affect up to 1 in 1,000 people): gastroenterological disorders such as inflammation of the intestines, vomiting, dry mouth, belching; urolithiasis; decreased platelet count; increased blood pressure.
In addition, severe liver disorders such as liver damage or biliary tract obstruction, as well as increased levels of liver enzymes in the blood (such as transaminase, alkaline phosphatase, bilirubin and gamma-glutamyl transpeptidase) may occur with an unknown frequency.
Method of administration
Adults are used orally.
Take 1 capsule once a day during a meal, washed down with one glass of water. The capsule should not be chewed.
If the drug is missed, the usual daily dose should be taken the next day, the dose should not be doubled. The duration of treatment with Piascledin® 300 is determined in accordance with the doctor’s recommendations.
Features of use
Use during pregnancy or breastfeeding
Studies on the use of the drug with the participation of pregnant women have not been conducted, therefore the drug is not recommended for use during pregnancy.
There is no information on the use of the drug during breastfeeding, so you should refrain from using the drug during this period.
Children
Piascledine 300 is used only by adults. Do not use this drug in children (under 18 years of age).
Ability to influence the speed of reactions when driving vehicles or other mechanisms
Piascledin 300 does not affect the ability to drive vehicles or work with other mechanisms.
Overdose
Using a dose of Piascledine 300 higher than prescribed may increase the risk of gastroenterological disorders or liver disorders. If you take a dose of Piascledin 300 higher than prescribed, you should immediately consult a doctor or pharmacist.
Interaction with other medicines and other types of interactions
You should inform your doctor or pharmacist about the simultaneous use of other medicines.
Piascledine 300 may affect anticoagulants or be affected by them.
Storage conditions
Store at a temperature not exceeding 25 °C.
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