Lidocaine spray 10% bottle 38 g

The active ingredient is lidocaine (1 bottle contains 3.8 g of lidocaine; one dose contains 4.8 mg of lidocaine).

Excipients: ethanol 96%, propylene glycol, peppermint oil.

• hypersensitivity to the components of the drug, as well as to other amide local anesthetic drugs;
• In dentistry, the use of the drug is contraindicated before using plaster due to the risk of aspiration.

For external use.

Remove the cap, attach the valve-dispenser and fill the bottle pump with solution before first use (press the pump several times until an aerosol appears in the air).

If the spray bottle has not been used for a long time, the pump may need to be refilled.

The dose of the drug depends on the indications and the size of the surface to be anesthetized.

With each spray of one portion of the spray, 4.8 mg of lidocaine (one dose) is released onto the surface.

In order to avoid high plasma concentrations, it is important to use the lowest dose that provides a satisfactory effect.

Approximate doses for various indications (dose – number of presses):

• dentistry – 1-3;
• maxillofacial surgery – 1-4;
• otolaryngology – 1-4;
• endoscopy – 2-3;
• obstetrics – 15-20;
• gynecology – 4-5;
• dermatology – 1-3.

Usually 1-2 sprays are sufficient, although in obstetrics 15-20 sprays or more are used (maximum dose – 40 sprays / 70 kg of body weight).

Using a cotton swab soaked in this preparation, the medicine can be applied to large surfaces.

Use in children: in dentistry or maxillofacial surgery, Lidocaine spray can be used in children by applying with a swab, which avoids the risk of inhalation of the drug and the burning sensation that usually occurs as a side effect of the drug. Children under 2 years of age can use the drug in the same way. The drug is not recommended for use for local anesthesia before tonsillectomy and adenoidectomy in children under 8 years of age. By suppressing the pharyngeal reflex and reaching the larynx and trachea (risk of aspiration), lidocaine suppresses the cough reflex, which can lead to bronchopneumonia.

Pregnant women

Strictly controlled clinical studies of the safety of the drug during pregnancy have not been conducted, however, “Lidocaine” has been used for a long time, and it did not harm the patient’s health. In preclinical studies, no toxic effects of lidocaine on fetal development were found. In the absence of a safer method of treatment, “Lidocaine” spray can also be used during pregnancy.

The drug is excreted in breast milk, however, when using normal therapeutic doses, the amount of the drug excreted is so small that it does not harm a breastfed child.

Drivers

Given that sensitive patients may experience adverse reactions from the central nervous system (excitement, depression, nervousness, dizziness, drowsiness, spasms, loss of consciousness, respiratory paralysis) when using the drug, you should refrain from driving vehicles and other work that requires concentration of attention while taking the drug.

Symptoms: increased sweating, pale skin, dizziness, headache, blurred vision, tinnitus, diplopia, decreased blood pressure, bradycardia, arrhythmia, drowsiness, chills, numbness of the extremities, anxiety, convulsions, shock, methemoglobinemia, cardiac arrest.

Treatment

If necessary, provide access to fresh air, oxygen and/or artificial respiration.

Convulsions resulting from overdose should be treated with succinylcholine (1 mg/kg body weight) and/or diazepam (1 mg/kg body weight intravenously). Since succinylcholine can cause respiratory arrest, it should only be used by specialists experienced in endotracheal intubation and the treatment of patients with respiratory arrest. Short-acting barbiturates and thiopental can also be used. If symptoms from the cardiovascular system appear (bradycardia, conduction disturbances), atropine (0.5-1 mg intravenously) and sympathomimetics should be administered. In case of ventricular fibrillation and cardiac arrest, immediate resuscitation measures are indicated.

Local effects: when using lidocaine, a burning sensation may occur, which disappears after the anesthetic effect appears (within one minute); transient erythema, edema, and decreased sensitivity may be observed at the site of application.

Allergic reactions: including: skin rash, itching, urticaria, angioedema, bronchospasm, in extremely severe cases – shock; in case of hypersensitivity reactions, the use of the drug should be discontinued.

Systemic effects: If this drug is used according to the instructions, the incidence of systemic effects is extremely low, since the amount of active substance that can reach the bloodstream is very small. When using high doses and in case of rapid absorption of lidocaine or in case of hypersensitivity, idiosyncrasy or reduced tolerance, the following side effects may develop:

• from the side of the central nervous system: excitement, depression, nervousness, dizziness, drowsiness, spasms, loss of consciousness, respiratory paralysis;
• Cardiovascular system: hypotension, myocardial infarction, bradycardia, cardiac arrest.

Store at a temperature not exceeding 25 °C, out of the reach of children.

Shelf life – 5 years.