Livarol pessaries (suppositories) 400 mg 10 pcs.

Active ingredient: ketoconazole;

1 pessary contains 400 mg of ketoconazole;

Excipients: butylhydroxyanisole (E 320), macrogol 1500, macrogol 400.

Hypersensitivity to the components of the drug, pregnancy (I trimester).

The drug is used vaginally. Before use, the pessary is removed from the contour packaging and inserted deep into the vagina in the supine position. 1 pessary is used per day for 3-5 days, depending on the course of the disease. If necessary, the course of treatment is repeated until clinical recovery, confirmed by laboratory tests. In chronic candidiasis, 1 pessary is used for 10 days.

During pregnancy (II-III trimester) and breastfeeding, the method of administration and doses are normal.

Pregnant women

Do not use in the first trimester of pregnancy. In the second and third trimesters of pregnancy and during breastfeeding, the drug is used only when the expected benefit to the mother outweighs the potential risk to the fetus or child.

Children

There is no experience with the use of the drug in children, so it should not be prescribed to this age group of patients.

Drivers

No effect.

Overdose and toxic effects when using the drug have not been identified.

Hyperemia and irritation of the vaginal mucosa, vaginal itching at the site of pessary insertion, and allergic reactions (skin rashes, urticaria) are possible.

In rare cases, nausea and dizziness may occur.

When Livarol is used simultaneously with rifampicin and isoniazid, the concentration of ketoconazole in plasma decreases. When used simultaneously with cyclosporine, indirect anticoagulants and methylprednisolone, ketoconazole may increase the concentration of the above-mentioned drugs in plasma. The practical significance of these interactions in treatment with ketoconazole in the form of vaginal pessaries is unknown.

Store in the original packaging at a temperature not exceeding 25 °C.

Keep out of reach of children.

Shelf life – 2 years.